Introduction
Chemical genomics is the process of screening for small molecule drugs that target a protein or system of interest. [1] In most drug discovery studies, a large library is introduced to cells that have the disease of interest. Naturally, the introduction of small molecule drugs will disrupt various cellular processes. Cells that exhibit the desired phenotype will be selected for further screening.
Discussion
A thorough search of the PubChem database showed that no known drugs interact with the NOG gene product. [3] However, that doesn't mean that such a drug does not exist. It simply means that treatment plans for TCC will not include a small molecule drug until such time that a chemical screen reveals an effective drug treatment.
References
[1] https://www.nature.com/subjects/chemical-genetics
[2] https://www.singerinstruments.com/resource/chemical-genetics-and-drug-target-discovery/
[3] https://pubchem.ncbi.nlm.nih.gov/gene/9241#section=Interactions-and-Pathways
[2] https://www.singerinstruments.com/resource/chemical-genetics-and-drug-target-discovery/
[3] https://pubchem.ncbi.nlm.nih.gov/gene/9241#section=Interactions-and-Pathways